Constantine Markides, Ph.D.

Education

• BPharm, Aristotelean University of Thessaloniki, Greece, 1995
• MS, Pharmacology & Toxicology, University of Texas Medical Branch, Galveston, 1998
• Ph.D.,  Pharmacology & Toxicology, University of Texas Medical Branch, Galveston, 2002

Post-doctoral Training

• CHRISTUS Stehlin Foundation for Cancer Research, 2005

Area of Interest

• Drug Development
• Topoisomerase I inhibitors
• Estrogen Carcinogenesis

Current Position

• Chief Pharmacologist, CHRISTUS Stehlin Foundation

Professional Organization Memberships

• American Association for Cancer Research
• Endocrine Society

Representative Publications

Markides, C.S.A., Olszewski, A.P., Muckleroy L., DeJesus A., Vardeman D.M., Giovanella B.C. 2009.  Characterization of the activation of the non-toxic prodrug CZ48: ultra-sensitive, simultaneous detection with CPT and tumor-specific in vitro activation. Proceedings of the 100th Annual AACR meeting

Markides, C.S.A, Liehr, J.G.  2005.  Specific binding of 4-hydroxyestradiol to mouse uterine protein: evidence of a physiological role for 4-hydroxyestradiol. J  Endocrinol. 185(2): 235-242

Markides, C.S.A., Liehr, J.G.  2002. Hormonal activity of 4-hydroxyestradiol: characterization of specific 4-hydroxyestradiol binding. Breast Cancer Research and Treatment 76 (S1): 369

Markides, C.S.A., Liehr, J.G.  2002.  Binding of the catecholestrogen, 4-hydroxyestradiol to a specific binding protein in uteri of Swiss NIH high fertility strain mice. Proceedings of the 84th Annual Endocrine Society Meeting, P2-462

Markides, C.S.A., Roy, D., Liehr, J.G.  1998.  Concentration Dependence of Prooxidant and Antioxidant Properties of Catecholestrogens. Arch Biochem Biophys. 360(1): 105-112

Markides, C.S.A., Liehr, J.G.  1997. Anti- and Pro-oxidant Effects of Catecholestrogens. The Pharmacologist 39(1): 113